Notes
Slide Show
Outline
1
Cell Membranes & Transport
  • Dan Rowe
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Introduction
  • Identify the Key elements which make up Plasma Membrane
  • Discuss the foundation of transport of medium through the Plasma Membrane
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Membrane Structure
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The Building Blocks of a Cell Membrane
  • Phospholipids
  • Membrane Bound Proteins
  • Glycoproteins
  • Transport Proteins
  • Cholesterol
  • Glycolipid
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The Role of the Membrane
  • Compartmentalisation within a cell
  • Containing Enzymes
  • Containing Cell Contents
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Phospholipids
  • Hydrophobic & Hydrophilic Regions (Polar)
  • Phosphate Group, Glycerol & 2 fatty acid tails
  • Creating a bi-layer
  • Saturation Effects
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Cholesterol
  • Regulating Fluidity
  • Also Polar
  • Mechanical Stability (Stops cells Bursting
  • Prevention of ions/polar molecules passing through the membrane (ie myelin sheath)
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The Role of Proteins
  • Pumps (ADP+Pi - ATP)
  • Adhesion Sites
  • Receptors
  • Channels (H2O Sol/Big)
  • Carriers (Charged Ions)
  • Antigens (Identification)
  • Enzymes (Faster reactions)
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Fluid Mosaic Model
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Transport Across The Membrane
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Diffusion & Channel Proteins
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Active Transport
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Bulk Transport -
Exocytosis & Endocytosis
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Exocytotic Vesicle Emptying at Cell Plasma Membrane
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Gaseous Exchange in the Mammalian Lung
  • Large Surface Area (50-70m2):Volume
  • 1 Cell Thick - Squamous Epithelium
  • Good Blood Supply
  • High O2 Gradient